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Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination
While regulating the choice between homologous recombination and non-homologous end joining (NHEJ) as mechanisms of double-strand break (DSB) repair is exerted at several steps, the key step is DNA end resection, which in Saccharomyces cerevisiae is controlled by the MRX complex and the Sgs1 DNA hel...
Autores principales: | Muñoz-Galván, Sandra, López-Saavedra, Ana, Jackson, Stephen P., Huertas, Pablo, Cortés-Ledesma, Felipe, Aguilera, Andrés |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561951/ https://www.ncbi.nlm.nih.gov/pubmed/23254329 http://dx.doi.org/10.1093/nar/gks1274 |
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