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Vaccinia and influenza A viruses select rather than adjust tRNAs to optimize translation

Transfer RNAs (tRNAs) are central to protein synthesis and impact translational speed and fidelity by their abundance. Here we examine the extent to which viruses manipulate tRNA populations to favor translation of their own genes. We study two very different viruses: influenza A virus (IAV), a medi...

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Detalles Bibliográficos
Autores principales: Pavon-Eternod, Mariana, David, Alexandre, Dittmar, Kimberly, Berglund, Peter, Pan, Tao, Bennink, Jack R., Yewdell, Jonathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561966/
https://www.ncbi.nlm.nih.gov/pubmed/23254333
http://dx.doi.org/10.1093/nar/gks986