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Decoupling nucleosome recognition from DNA binding dramatically alters the properties of the Chd1 chromatin remodeler
Chromatin remodelers can either organize or disrupt nucleosomal arrays, yet the mechanisms specifying these opposing actions are not clear. Here, we show that the outcome of nucleosome sliding by Chd1 changes dramatically depending on how the chromatin remodeler is targeted to nucleosomes. Using a C...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561990/ https://www.ncbi.nlm.nih.gov/pubmed/23275572 http://dx.doi.org/10.1093/nar/gks1440 |