Decoupling nucleosome recognition from DNA binding dramatically alters the properties of the Chd1 chromatin remodeler

Chromatin remodelers can either organize or disrupt nucleosomal arrays, yet the mechanisms specifying these opposing actions are not clear. Here, we show that the outcome of nucleosome sliding by Chd1 changes dramatically depending on how the chromatin remodeler is targeted to nucleosomes. Using a C...

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Detalles Bibliográficos
Autores principales: Patel, Ashok, Chakravarthy, Srinivas, Morrone, Seamus, Nodelman, Ilana M., McKnight, Jeffrey N., Bowman, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561990/
https://www.ncbi.nlm.nih.gov/pubmed/23275572
http://dx.doi.org/10.1093/nar/gks1440

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