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Sleeping Beauty transposon-based system for cellular reprogramming and targeted gene insertion in induced pluripotent stem cells

The discovery of direct cell reprogramming and induced pluripotent stem (iPS) cell technology opened up new avenues for the application of non-viral, transposon-based gene delivery systems. The Sleeping Beauty (SB) transposon is highly advanced for versatile genetic manipulations in mammalian cells....

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Detalles Bibliográficos
Autores principales: Grabundzija, Ivana, Wang, Jichang, Sebe, Attila, Erdei, Zsuzsanna, Kajdi, Robert, Devaraj, Anantharam, Steinemann, Doris, Szuhai, Károly, Stein, Ulrike, Cantz, Tobias, Schambach, Axel, Baum, Christopher, Izsvák, Zsuzsanna, Sarkadi, Balázs, Ivics, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561994/
https://www.ncbi.nlm.nih.gov/pubmed/23275558
http://dx.doi.org/10.1093/nar/gks1305