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Volatility in mRNA secondary structure as a design principle for antisense
Designing effective antisense sequences is a formidable problem. A method for predicting efficacious antisense holds the potential to provide fundamental insight into this biophysical process. More practically, such an understanding increases the chance of successful antisense design as well as savi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562002/ https://www.ncbi.nlm.nih.gov/pubmed/23161691 http://dx.doi.org/10.1093/nar/gks902 |