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Inference of gene regulatory networks from genome-wide knockout fitness data

Motivation: Genome-wide fitness is an emerging type of high-throughput biological data generated for individual organisms by creating libraries of knockouts, subjecting them to broad ranges of environmental conditions, and measuring the resulting clone-specific fitnesses. Since fitness is an organis...

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Detalles Bibliográficos
Autores principales: Wang, Liming, Wang, Xiaodong, Arkin, Adam P., Samoilov, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562072/
https://www.ncbi.nlm.nih.gov/pubmed/23271269
http://dx.doi.org/10.1093/bioinformatics/bts634