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Preclinical evaluation of Sunitinib as a single agent in the prophylactic setting in a mouse model of bone metastases

BACKGROUND: A substantial number of breast cancer patients are identified as being at high risk of developing metastatic disease. With increasing number of targeted therapeutics entering clinical trials, chronic administration of these agents may be a feasible approach for the prevention of metastas...

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Detalles Bibliográficos
Autores principales: Schem, Christian, Bauerschlag, Dirk, Bender, Sascha, Lorenzen, Ann-Christin, Loermann, Daniel, Hamann, Sigrid, Rösel, Frank, Kalthoff, Holger, Glüer, Claus C, Jonat, Walter, Tiwari, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562143/
https://www.ncbi.nlm.nih.gov/pubmed/23347638
http://dx.doi.org/10.1186/1471-2407-13-32