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Integrin-mediated internalization of Staphylococcus aureus does not require vinculin

BACKGROUND: Disease manifestations of Staphylococcus aureus are connected to the fibronectin (Fn)-binding capacity of these Gram-positive pathogens. Fn deposition on the surface of S. aureus allows engagement of α5β1 integrins and triggers uptake by host cells. For several integrin- and actin-associ...

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Detalles Bibliográficos
Autores principales: Borisova, Marina, Shi, Yong, Buntru, Alexander, Wörner, Susanne, Ziegler, Wolfgang H, Hauck, Christof R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562162/
https://www.ncbi.nlm.nih.gov/pubmed/23294665
http://dx.doi.org/10.1186/1471-2121-14-2