Rescue of nonsense mutations by amlexanox in human cells

BACKGROUND: Nonsense mutations are at the origin of many cancers and inherited genetic diseases. The consequence of nonsense mutations is often the absence of mutant gene expression due to the activation of an mRNA surveillance mechanism called nonsense-mediated mRNA decay (NMD). Strategies to rescu...

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Detalles Bibliográficos
Autores principales: Gonzalez-Hilarion, Sara, Beghyn, Terence, Jia, Jieshuang, Debreuck, Nadège, Berte, Gonzague, Mamchaoui, Kamel, Mouly, Vincent, Gruenert, Dieter C, Déprez, Benoit, Lejeune, Fabrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562214/
https://www.ncbi.nlm.nih.gov/pubmed/22938201
http://dx.doi.org/10.1186/1750-1172-7-58

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562214/
https://www.ncbi.nlm.nih.gov/pubmed/22938201
http://dx.doi.org/10.1186/1750-1172-7-58

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