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Frequency and Prognostic Impact of CEBPA Proximal, Distal and Core Promoter Methylation in Normal Karyotype AML: A Study on 623 Cases
The clinical impact of aberrant CEBPA promoter methylation (PM) in AML is controversially discussed. The aim of this study was to clarify the significance of aberrant CEBPA PM with regard to clinical features in a cohort of 623 cytogenetically normal (CN) de novo AML. 555 cases had wild-type CEBPA,...
Autores principales: | Fasan, Annette, Alpermann, Tamara, Haferlach, Claudia, Grossmann, Vera, Roller, Andreas, Kohlmann, Alexander, Eder, Christiane, Kern, Wolfgang, Haferlach, Torsten, Schnittger, Susanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562230/ https://www.ncbi.nlm.nih.gov/pubmed/23383300 http://dx.doi.org/10.1371/journal.pone.0054365 |
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