Chronic TLR Signaling Impairs the Long-Term Repopulating Potential of Hematopoietic Stem Cells of Wild Type but Not Id1 Deficient Mice

Hematopoietic stem cells (HSCs) maintain life-long blood supply but are inevitably exposed to various inflammatory stimuli, which have been shown to be harmful for HSC integrity but the mediators of the deleterious effects have not been fully identified. Here, we show that daily injection of mice wi...

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Detalles Bibliográficos
Autores principales: Zhao, Ying, Ling, Flora, Wang, Hong-Cheng, Sun, Xiao-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562238/
https://www.ncbi.nlm.nih.gov/pubmed/23383338
http://dx.doi.org/10.1371/journal.pone.0055552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562238/
https://www.ncbi.nlm.nih.gov/pubmed/23383338
http://dx.doi.org/10.1371/journal.pone.0055552

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