Choline-releasing glycerophosphodiesterase EDI3 links the tumor metabolome to signaling network activities

Recently, EDI3 was identified as a key factor for choline metabolism that controls tumor cell migration and is associated with metastasis in endometrial carcinomas. EDI3 cleaves glycerophosphocholine (GPC) to form choline and glycerol-3-phosphate (G3P). Choline is then further metabolized to phospha...

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Detalles Bibliográficos
Autores principales: Marchan, Rosemarie, Lesjak, Michaela S., Stewart, Joanna D., Winter, Roland, Seeliger, Janine, Hengstler, Jan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562293/
https://www.ncbi.nlm.nih.gov/pubmed/23114620
http://dx.doi.org/10.4161/cc.22544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562293/
https://www.ncbi.nlm.nih.gov/pubmed/23114620
http://dx.doi.org/10.4161/cc.22544

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