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Choline-releasing glycerophosphodiesterase EDI3 links the tumor metabolome to signaling network activities
Recently, EDI3 was identified as a key factor for choline metabolism that controls tumor cell migration and is associated with metastasis in endometrial carcinomas. EDI3 cleaves glycerophosphocholine (GPC) to form choline and glycerol-3-phosphate (G3P). Choline is then further metabolized to phospha...
Autores principales: | Marchan, Rosemarie, Lesjak, Michaela S., Stewart, Joanna D., Winter, Roland, Seeliger, Janine, Hengstler, Jan G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562293/ https://www.ncbi.nlm.nih.gov/pubmed/23114620 http://dx.doi.org/10.4161/cc.22544 |
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