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Human CLPP reverts the longevity phenotype of a fungal ClpP deletion strain
Mitochondrial maintenance crucially depends on the quality control of proteins by various chaperones, proteases and repair enzymes. While most of the involved components have been studied in some detail, little is known on the biological role of the CLPXP protease complex located in the mitochondria...
Autores principales: | Fischer, Fabian, Weil, Andrea, Hamann, Andrea, Osiewacz, Heinz D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562451/ https://www.ncbi.nlm.nih.gov/pubmed/23360988 http://dx.doi.org/10.1038/ncomms2397 |
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