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Signalling properties of inorganic polyphosphate in the mammalian brain

Inorganic polyphosphate is known to be present in the mammalian brain at micromolar concentrations. Here we show that polyphosphate may act as a gliotransmitter, mediating communication between astrocytes. It is released by astrocytes in a calcium-dependent manner and signals to neighbouring astrocy...

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Detalles Bibliográficos
Autores principales: Holmström, Kira M., Marina, Nephtali, Baev, Artyom Y., Wood, Nicholas W., Gourine, Alexander V., Abramov, Andrey Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562455/
https://www.ncbi.nlm.nih.gov/pubmed/23322050
http://dx.doi.org/10.1038/ncomms2364