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Interplay between myosin IIA-mediated contractility and actin network integrity orchestrates podosome composition and oscillations

Tissue-resident dendritic cells patrol for foreign antigens while undergoing slow mesenchymal migration. Using actomyosin-based structures called podosomes, dendritic cells probe and remodel extracellular matrix topographical cues. Podosomes comprise an actin-rich protrusive core surrounded by an ad...

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Detalles Bibliográficos
Autores principales: van den Dries, K., Meddens, M.B.M, de Keijzer, S., Shekhar, S., Subramaniam, V., Figdor, C.G., Cambi, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562466/
https://www.ncbi.nlm.nih.gov/pubmed/23361003
http://dx.doi.org/10.1038/ncomms2402