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Radiosensitizing effect of intratumoral interleukin-12 gene electrotransfer in murine sarcoma

BACKGROUND: Interleukin-12 (IL-12) based radiosensitization is an effective way of tumor treatment. Local cytokine production, without systemic shedding, might provide clinical benefit in radiation treatment of sarcomas. Therefore, the aim was to stimulate intratumoral IL-12 production by gene elect...

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Detalles Bibliográficos
Autores principales: Sedlar, Ales, Kranjc, Simona, Dolinsek, Tanja, Cemazar, Maja, Coer, Andrej, Sersa, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562515/
https://www.ncbi.nlm.nih.gov/pubmed/23360213
http://dx.doi.org/10.1186/1471-2407-13-38