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Improved Insulin Sensitivity during Pioglitazone Treatment Is Associated with Changes in IGF-I and Cortisol Secretion in Type 2 Diabetes and Impaired Glucose Tolerance

Background. Hypercortisolism and type 2 diabetes (T2D) share clinical characteristics. We examined pioglitazone's effects on the GH-IGF-I and HPA axes in men with varying glucose intolerance. Methods. 10 men with T2D and 10 with IGT received pioglitazone 30–45 mg for 12 weeks. OGTT with microdi...

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Detalles Bibliográficos
Autores principales: Arnetz, Lisa, Rajamand Ekberg, Neda, Höybye, Charlotte, Brismar, Kerstin, Alvarsson, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562586/
https://www.ncbi.nlm.nih.gov/pubmed/23401789
http://dx.doi.org/10.1155/2013/148497