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Exploiting protein flexibility to predict the location of allosteric sites
BACKGROUND: Allostery is one of the most powerful and common ways of regulation of protein activity. However, for most allosteric proteins identified to date the mechanistic details of allosteric modulation are not yet well understood. Uncovering common mechanistic patterns underlying allostery woul...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562710/ https://www.ncbi.nlm.nih.gov/pubmed/23095452 http://dx.doi.org/10.1186/1471-2105-13-273 |