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Exploiting protein flexibility to predict the location of allosteric sites

BACKGROUND: Allostery is one of the most powerful and common ways of regulation of protein activity. However, for most allosteric proteins identified to date the mechanistic details of allosteric modulation are not yet well understood. Uncovering common mechanistic patterns underlying allostery woul...

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Detalles Bibliográficos
Autores principales: Panjkovich, Alejandro, Daura, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562710/
https://www.ncbi.nlm.nih.gov/pubmed/23095452
http://dx.doi.org/10.1186/1471-2105-13-273