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Role of CXCR4 in the Pathogenesis of Acute Myeloid Leukemia

The Chemokine receptor CXCR4 and its ligand stromal derived factor-1 (SDF-1/CXCL12) are important players involved in cross-talk between leukemia cells and the bone marrow (BM) microenvironment. CXCR4 expression is associated with poor prognosis in AML patients with and without the mutated FLT3 gene...

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Detalles Bibliográficos
Autores principales:	Peled, Amnon, Tavor, Sigal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563079/ https://www.ncbi.nlm.nih.gov/pubmed/23382784 http://dx.doi.org/10.7150/thno.5150

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