Role of CXCR4 in the Pathogenesis of Acute Myeloid Leukemia
The Chemokine receptor CXCR4 and its ligand stromal derived factor-1 (SDF-1/CXCL12) are important players involved in cross-talk between leukemia cells and the bone marrow (BM) microenvironment. CXCR4 expression is associated with poor prognosis in AML patients with and without the mutated FLT3 gene...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Ivyspring International Publisher
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563079/ https://www.ncbi.nlm.nih.gov/pubmed/23382784 http://dx.doi.org/10.7150/thno.5150 |