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Targeting the CXCL12/CXCR4 axis in acute myeloid leukemia: from bench to bedside

The interactions between the cancerous cells of acute myeloid leukemia (AML) and the bone marrow (BM) microenvironment have been postulated to be important for resistance to chemotherapy and disease relapse in AML. The chemokine receptor CXC chemokine receptor 4 (CXCR4) and its ligand, CXC motif lig...

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Detalles Bibliográficos
Autores principales: Cho, Byung-Sik, Kim, Hee-Je, Konopleva, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339474/
https://www.ncbi.nlm.nih.gov/pubmed/28219003
http://dx.doi.org/10.3904/kjim.2016.244