Anabolic effects of IGF-1 signaling on the skeleton

This review focuses on the anabolic effects of IGF-1 signaling on the skeleton, emphasizing the requirement for IGF-1 signaling in normal bone formation and remodeling. We first discuss the genomic context, splicing variants, and species conservation of the IGF-1 locus. The modulation of IGF-1 actio...

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Detalles Bibliográficos
Autores principales: Tahimic, Candice G. T., Wang, Yongmei, Bikle, Daniel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563099/
https://www.ncbi.nlm.nih.gov/pubmed/23382729
http://dx.doi.org/10.3389/fendo.2013.00006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563099/
https://www.ncbi.nlm.nih.gov/pubmed/23382729
http://dx.doi.org/10.3389/fendo.2013.00006

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