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Anabolic effects of IGF-1 signaling on the skeleton

This review focuses on the anabolic effects of IGF-1 signaling on the skeleton, emphasizing the requirement for IGF-1 signaling in normal bone formation and remodeling. We first discuss the genomic context, splicing variants, and species conservation of the IGF-1 locus. The modulation of IGF-1 actio...

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Detalles Bibliográficos
Autores principales:	Tahimic, Candice G. T., Wang, Yongmei, Bikle, Daniel D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563099/ https://www.ncbi.nlm.nih.gov/pubmed/23382729 http://dx.doi.org/10.3389/fendo.2013.00006

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