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A two-step drug repositioning method based on a protein-protein interaction network of genes shared by two diseases and the similarity of drugs

The present study proposed a two-step drug repositioning method based on a protein-protein interaction (PPI) network of two diseases and the similarity of the drugs prescribed for one of the two. In the proposed method, first, lists of disease related genes were obtained from a meta-database called...

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Detalles Bibliográficos
Autores principales: Fukuoka, Yutaka, Takei, Daiki, Ogawa, Hisamichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563404/
https://www.ncbi.nlm.nih.gov/pubmed/23390352
http://dx.doi.org/10.6026/97320630009089