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Role of highly central residues of P-loop and it's flanking region in preserving the archetypal conformation of Walker A motif of diverse P-loop NTPases

P-loop NTPases represent a large and highly diverse protein family that is involved in variety of cellular functions. Walker A motif forms a typical arched conformation, necessary to accommodate the phosphate moiety of the nucleoside tri (or di-) phosphate in Ploop NTPases. The feature that maintain...

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Detalles Bibliográficos
Autores principales: Pathak, Ekta, Atri, Neelam, Mishra, Rajeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563412/
https://www.ncbi.nlm.nih.gov/pubmed/23390340
http://dx.doi.org/10.6026/97320630009023