Different mutations of the human c-mpl gene indicate distinct haematopoietic diseases

The human c-mpl gene (MPL) plays an important role in the development of megakaryocytes and platelets as well as the self-renewal of haematopoietic stem cells. However, numerous MPL mutations have been identified in haematopoietic diseases. These mutations alter the normal regulatory mechanisms and...

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Detalles Bibliográficos
Autores principales: He, Xin, Chen, Zhigang, Jiang, Yangyan, Qiu, Xi, Zhao, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563459/
https://www.ncbi.nlm.nih.gov/pubmed/23351976
http://dx.doi.org/10.1186/1756-8722-6-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563459/
https://www.ncbi.nlm.nih.gov/pubmed/23351976
http://dx.doi.org/10.1186/1756-8722-6-11

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