Cargando…

Denoising PCR-amplified metagenome data

BACKGROUND: PCR amplification and high-throughput sequencing theoretically enable the characterization of the finest-scale diversity in natural microbial and viral populations, but each of these methods introduces random errors that are difficult to distinguish from genuine biological diversity. Sev...

Descripción completa

Detalles Bibliográficos
Autores principales: Rosen, Michael J, Callahan, Benjamin J, Fisher, Daniel S, Holmes, Susan P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563472/
https://www.ncbi.nlm.nih.gov/pubmed/23113967
http://dx.doi.org/10.1186/1471-2105-13-283