Improving mapping and SNP-calling performance in multiplexed targeted next-generation sequencing

BACKGROUND: Compared to classical genotyping, targeted next-generation sequencing (tNGS) can be custom-designed to interrogate entire genomic regions of interest, in order to detect novel as well as known variants. To bring down the per-sample cost, one approach is to pool barcoded NGS libraries bef...

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Detalles Bibliográficos
Autores principales: ElSharawy, Abdou, Forster, Michael, Schracke, Nadine, Keller, Andreas, Thomsen, Ingo, Petersen, Britt-Sabina, Stade, Björn, Stähler, Peer, Schreiber, Stefan, Rosenstiel, Philip, Franke, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563481/
https://www.ncbi.nlm.nih.gov/pubmed/22913592
http://dx.doi.org/10.1186/1471-2164-13-417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563481/
https://www.ncbi.nlm.nih.gov/pubmed/22913592
http://dx.doi.org/10.1186/1471-2164-13-417

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