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Impact of constitutional copy number variants on biological pathway evolution

BACKGROUND: Inherited Copy Number Variants (CNVs) can modulate the expression levels of individual genes. However, little is known about how CNVs alter biological pathways and how this varies across different populations. To trace potential evolutionary changes of well-described biological pathways,...

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Detalles Bibliográficos
Autores principales: Poptsova, Maria, Banerjee, Samprit, Gokcumen, Omer, Rubin, Mark A, Demichelis, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563492/
https://www.ncbi.nlm.nih.gov/pubmed/23342974
http://dx.doi.org/10.1186/1471-2148-13-19