Comparative modeling and docking studies of p16ink4/Cyclin D1/Rb pathway genes in lung cancer revealed functionally interactive residue of RB1 and its functional partner E2F1

BACKGROUND: Lung cancer is the major cause of mortality worldwide. Major signalling pathways that could play significant role in lung cancer therapy include (1) Growth promoting pathways (Epidermal Growth Factor Receptor/Ras/ PhosphatidylInositol 3-Kinase) (2) Growth inhibitory pathways (p53/Rb/P14A...

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Detalles Bibliográficos
Autores principales: e Zahra, Syeda Naqsh, Khattak, Naureen Aslam, Mir, Asif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563505/
https://www.ncbi.nlm.nih.gov/pubmed/23276293
http://dx.doi.org/10.1186/1742-4682-10-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563505/
https://www.ncbi.nlm.nih.gov/pubmed/23276293
http://dx.doi.org/10.1186/1742-4682-10-1

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