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Potential contribution of SIM2 and ETS2 functional polymorphisms in Down syndrome associated malignancies

BACKGROUND: Proper expression and functioning of transcription factors (TFs) are essential for regulation of different traits and thus could be crucial for the development of complex diseases. Subjects with Down syndrome (DS) have a higher incidence of acute lymphoblastic leukemia (ALL) while solid...

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Detalles Bibliográficos
Autores principales: Chatterjee, Arpita, Dutta, Samikshan, Mukherjee, Sanjit, Mukherjee, Nupur, Dutta, Avirup, Mukherjee, Ashis, Sinha, Swagata, Panda, Chinmay Kumar, Chaudhuri, Keya, Roy, Ananda L, Mukhopadhyay, Kanchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563522/
https://www.ncbi.nlm.nih.gov/pubmed/23343470
http://dx.doi.org/10.1186/1471-2350-14-12