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Potential contribution of SIM2 and ETS2 functional polymorphisms in Down syndrome associated malignancies
BACKGROUND: Proper expression and functioning of transcription factors (TFs) are essential for regulation of different traits and thus could be crucial for the development of complex diseases. Subjects with Down syndrome (DS) have a higher incidence of acute lymphoblastic leukemia (ALL) while solid...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563522/ https://www.ncbi.nlm.nih.gov/pubmed/23343470 http://dx.doi.org/10.1186/1471-2350-14-12 |