Intravenous Delivery of HIV-Based Lentiviral Vectors Preferentially Transduces F4/80+ and Ly-6C+ Cells in Spleen, Important Target Cells in Autoimmune Arthritis

Antigen presenting cells (APCs) play an important role in arthritis and APC specific gene therapeutic targeting will enable intracellular modulation of cell activity. Viral mediated overexpression is a potent approach to achieve adequate transgene expression levels and lentivirus (LV) is useful for...

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Detalles Bibliográficos
Autores principales: van den Brand, Ben T., Vermeij, Eline A., Waterborg, Claire E. J., Arntz, Onno J., Kracht, Michael, Bennink, Miranda B., van den Berg, Wim B., van de Loo, Fons A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563527/
https://www.ncbi.nlm.nih.gov/pubmed/23390530
http://dx.doi.org/10.1371/journal.pone.0055356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563527/
https://www.ncbi.nlm.nih.gov/pubmed/23390530
http://dx.doi.org/10.1371/journal.pone.0055356

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