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Ultrashort Cationic Lipopeptides and Lipopeptoids Selectively Induce Cytokine Production in Macrophages

A series of ultrashort lipopeptides and lipopeptoids were tested for their ability to induce cytokine production in macrophages. Fourteen compounds were found to strongly induce production of chemokines Groα and IL-8, with a structural bias that was absent from previous antibacterial activity invest...

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Detalles Bibliográficos
Autores principales: Findlay, Brandon, Mookherjee, Neeloffer, Schweizer, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563528/
https://www.ncbi.nlm.nih.gov/pubmed/23390497
http://dx.doi.org/10.1371/journal.pone.0054280