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ZnT8-Specific CD4(+) T Cells Display Distinct Cytokine Expression Profiles between Type 1 Diabetes Patients and Healthy Adults

Determination of antigen-specific T cell repertoires in human blood has been a challenge. Here, we show a novel integrated approach that permits determination of multiple parameters of antigen-specific T cell repertoires. The approach consists of two assays: the Direct assay and the Cytokine-driven...

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Detalles Bibliográficos
Autores principales: Chujo, Daisuke, Foucat, Emile, Nguyen, Thien-Son, Chaussabel, Damien, Banchereau, Jacques, Ueno, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563599/
https://www.ncbi.nlm.nih.gov/pubmed/23390544
http://dx.doi.org/10.1371/journal.pone.0055595