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ZnT8-Specific CD4(+) T Cells Display Distinct Cytokine Expression Profiles between Type 1 Diabetes Patients and Healthy Adults
Determination of antigen-specific T cell repertoires in human blood has been a challenge. Here, we show a novel integrated approach that permits determination of multiple parameters of antigen-specific T cell repertoires. The approach consists of two assays: the Direct assay and the Cytokine-driven...
Autores principales: | Chujo, Daisuke, Foucat, Emile, Nguyen, Thien-Son, Chaussabel, Damien, Banchereau, Jacques, Ueno, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563599/ https://www.ncbi.nlm.nih.gov/pubmed/23390544 http://dx.doi.org/10.1371/journal.pone.0055595 |
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