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Astrocytic Ca(2+) signals are required for the functional integrity of tripartite synapses

BACKGROUND: Neuronal activity alters calcium ion (Ca(2+)) dynamics in astrocytes, but the physiologic relevance of these changes is controversial. To examine this issue further, we generated an inducible transgenic mouse model in which the expression of an inositol 1,4,5-trisphosphate absorbent, “IP...

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Detalles Bibliográficos
Autores principales: Tanaka, Mika, Shih, Pei-Yu, Gomi, Hiroshi, Yoshida, Takamasa, Nakai, Junichi, Ando, Reiko, Furuichi, Teiichi, Mikoshiba, Katsuhiko, Semyanov, Alexey, Itohara, Shigeyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563617/
https://www.ncbi.nlm.nih.gov/pubmed/23356992
http://dx.doi.org/10.1186/1756-6606-6-6