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Astrocytic Ca(2+) signals are required for the functional integrity of tripartite synapses
BACKGROUND: Neuronal activity alters calcium ion (Ca(2+)) dynamics in astrocytes, but the physiologic relevance of these changes is controversial. To examine this issue further, we generated an inducible transgenic mouse model in which the expression of an inositol 1,4,5-trisphosphate absorbent, “IP...
Autores principales: | Tanaka, Mika, Shih, Pei-Yu, Gomi, Hiroshi, Yoshida, Takamasa, Nakai, Junichi, Ando, Reiko, Furuichi, Teiichi, Mikoshiba, Katsuhiko, Semyanov, Alexey, Itohara, Shigeyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563617/ https://www.ncbi.nlm.nih.gov/pubmed/23356992 http://dx.doi.org/10.1186/1756-6606-6-6 |
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