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Comprehensive microRNA profiling in B-cells of human centenarians by massively parallel sequencing

BACKGROUND: MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression and play a critical role in development, homeostasis, and disease. Despite their demonstrated roles in age-associated pathologies, little is known about the role of miRNAs in human aging and longevity. RESULTS: W...

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Detalles Bibliográficos
Autores principales: Gombar, Saurabh, Jung, Hwa Jin, Dong, Feng, Calder, Brent, Atzmon, Gil, Barzilai, Nir, Tian, Xiao-Li, Pothof, Joris, Hoeijmakers, Jan HJ, Campisi, Judith, Vijg, Jan, Suh, Yousin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563618/
https://www.ncbi.nlm.nih.gov/pubmed/22846614
http://dx.doi.org/10.1186/1471-2164-13-353