Effects of SGLT2 Inhibition in Human Kidney Proximal Tubular Cells—Renoprotection in Diabetic Nephropathy?

Sodium/glucose cotransporter 2 (SGLT2) inhibitors are oral hypoglycemic agents used to treat patients with diabetes mellitus. SGLT2 inhibitors block reabsorption of filtered glucose by inhibiting SGLT2, the primary glucose transporter in the proximal tubular cell (PTC), leading to glycosuria and low...

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Detalles Bibliográficos
Autores principales: Panchapakesan, Usha, Pegg, Kate, Gross, Simon, Komala, Muralikrishna Gangadharan, Mudaliar, Harshini, Forbes, Josephine, Pollock, Carol, Mather, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563635/
https://www.ncbi.nlm.nih.gov/pubmed/23390498
http://dx.doi.org/10.1371/journal.pone.0054442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563635/
https://www.ncbi.nlm.nih.gov/pubmed/23390498
http://dx.doi.org/10.1371/journal.pone.0054442

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