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Dependency of Calcium Alternans on Ryanodine Receptor Refractoriness

BACKGROUND: Rapid pacing rates induce alternations in the cytosolic calcium concentration caused by fluctuations in calcium released from the sarcoplasmic reticulum (SR). However, the relationship between calcium alternans and refractoriness of the SR calcium release channel (RyR2) remains elusive....

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Detalles Bibliográficos
Autores principales: Alvarez-Lacalle, Enric, Cantalapiedra, Inma R., Peñaranda, Angelina, Cinca, Juan, Hove-Madsen, Leif, Echebarria, Blas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563653/
https://www.ncbi.nlm.nih.gov/pubmed/23390511
http://dx.doi.org/10.1371/journal.pone.0055042