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Dependency of Calcium Alternans on Ryanodine Receptor Refractoriness
BACKGROUND: Rapid pacing rates induce alternations in the cytosolic calcium concentration caused by fluctuations in calcium released from the sarcoplasmic reticulum (SR). However, the relationship between calcium alternans and refractoriness of the SR calcium release channel (RyR2) remains elusive....
Autores principales: | Alvarez-Lacalle, Enric, Cantalapiedra, Inma R., Peñaranda, Angelina, Cinca, Juan, Hove-Madsen, Leif, Echebarria, Blas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563653/ https://www.ncbi.nlm.nih.gov/pubmed/23390511 http://dx.doi.org/10.1371/journal.pone.0055042 |
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