Myosin VI small insert isoform maintains exocytosis by tethering secretory granules to the cortical actin

Before undergoing neuroexocytosis, secretory granules (SGs) are mobilized and tethered to the cortical actin network by an unknown mechanism. Using an SG pull-down assay and mass spectrometry, we found that myosin VI was recruited to SGs in a Ca(2+)-dependent manner. Interfering with myosin VI funct...

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Detalles Bibliográficos
Autores principales: Tomatis, Vanesa M., Papadopulos, Andreas, Malintan, Nancy T., Martin, Sally, Wallis, Tristan, Gormal, Rachel S., Kendrick-Jones, John, Buss, Folma, Meunier, Frédéric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563687/
https://www.ncbi.nlm.nih.gov/pubmed/23382463
http://dx.doi.org/10.1083/jcb.201204092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563687/
https://www.ncbi.nlm.nih.gov/pubmed/23382463
http://dx.doi.org/10.1083/jcb.201204092

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