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Glucose and SIRT2 reciprocally mediate the regulation of keratin 8 by lysine acetylation

Lysine acetylation is an important posttranslational modification that regulates microtubules and microfilaments, but its effects on intermediate filament proteins (IFs) are unknown. We investigated the regulation of keratin 8 (K8), a type II simple epithelial IF, by lysine acetylation. K8 was basal...

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Detalles Bibliográficos
Autores principales: Snider, Natasha T., Leonard, Jessica M., Kwan, Raymond, Griggs, Nicholas W., Rui, Liangyou, Omary, M. Bishr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563689/
https://www.ncbi.nlm.nih.gov/pubmed/23358244
http://dx.doi.org/10.1083/jcb.201209028