Remarkable stability of an instability-prone lentiviral vector plasmid in Escherichia coli Stbl3

Large-scale production of plasmid DNA to prepare therapeutic gene vectors or DNA-based vaccines requires a suitable bacterial host, which can stably maintain the plasmid DNA during industrial cultivation. Plasmid loss during bacterial cell divisions and structural changes in the plasmid DNA can dram...

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Detalles Bibliográficos
Autores principales: Al-Allaf, Faisal A., Tolmachov, Oleg E., Zambetti, Lia Paola, Tchetchelnitski, Viktoria, Mehmet, Huseyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563744/
https://www.ncbi.nlm.nih.gov/pubmed/28324350
http://dx.doi.org/10.1007/s13205-012-0070-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563744/
https://www.ncbi.nlm.nih.gov/pubmed/28324350
http://dx.doi.org/10.1007/s13205-012-0070-8

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