Cargando…
Remarkable stability of an instability-prone lentiviral vector plasmid in Escherichia coli Stbl3
Large-scale production of plasmid DNA to prepare therapeutic gene vectors or DNA-based vaccines requires a suitable bacterial host, which can stably maintain the plasmid DNA during industrial cultivation. Plasmid loss during bacterial cell divisions and structural changes in the plasmid DNA can dram...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563744/ https://www.ncbi.nlm.nih.gov/pubmed/28324350 http://dx.doi.org/10.1007/s13205-012-0070-8 |