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Human MicroRNAs Originated from Two Periods at Accelerated Rates in Mammalian Evolution

MicroRNAs (miRNAs) are short, noncoding RNAs that modulate genes posttranscriptionally. Frequent gains and losses of miRNA genes have been reported to occur during evolution. However, little is known systematically about the periods of evolutionary origin of the present miRNA gene repertoire of an e...

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Detalles Bibliográficos
Autores principales: Iwama, Hisakazu, Kato, Kiyohito, Imachi, Hitomi, Murao, Koji, Masaki, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563971/
https://www.ncbi.nlm.nih.gov/pubmed/23171859
http://dx.doi.org/10.1093/molbev/mss262