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Inhibition of Ephrin B3-mediated survival signaling contributes to increased cell death response of non-small cell lung carcinoma cells after combined treatment with ionizing radiation and PKC 412

Radiation therapy is frequently used to treat non-small cell lung cancers (NSCLCs). We have previously shown that a combination of ionizing radiation (IR) and the staurosporine analog PKC 412, but not Ro 31–8220, increases cell death in NSCLC cells. To identify genes involved in the enhancement of c...

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Detalles Bibliográficos
Autores principales: Ståhl, S, Kaminskyy, V O, Efazat, G, Hyrslova Vaculova, A, Rodriguez-Nieto, S, Moshfegh, A, Lewensohn, R, Viktorsson, K, Zhivotovsky, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563978/
https://www.ncbi.nlm.nih.gov/pubmed/23303128
http://dx.doi.org/10.1038/cddis.2012.188