Bak apoptotic function is not directly regulated by phosphorylation

During apoptosis, Bak and Bax permeabilize the mitochondrial outer membrane by undergoing major conformational change and oligomerization. This activation process in Bak is reported to require dephosphorylation of tyrosine-108 close to an activation trigger site. To investigate how dephosphorylation...

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Detalles Bibliográficos
Autores principales: Tran, V H, Bartolo, R, Westphal, D, Alsop, A, Dewson, G, Kluck, R M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563979/
https://www.ncbi.nlm.nih.gov/pubmed/23303126
http://dx.doi.org/10.1038/cddis.2012.191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563979/
https://www.ncbi.nlm.nih.gov/pubmed/23303126
http://dx.doi.org/10.1038/cddis.2012.191

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